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Published on December 28, 2023

HHC, HHCP, and HHC-O: A Comparative Analysis

The legal cannabis industry has witnessed the rise of various cannabinoids in recent years, and one such compound making waves is Hexahydrocannabinol, or HHC. Similar to its predecessor, Delta 8 THC, HHC has garnered attention for its intriguing properties and potential benefits. Alongside HHC, there are also its derivatives, HHC-P and HHC-O, each offering a unique experience within the realm of cannabinoids. In this article, we will delve into the distinctions between HHC, HHCP, and HHC-O, shedding light on their characteristics and potential uses.

HHC: A Brief Overview

Hexahydrocannabinol, or HHC, is a naturally-occurring phytocannabinoid found in hemp, albeit in trace amounts. However, direct extraction of HHC from hemp is not a practical or cost-effective process. Instead, manufacturers utilize hydrogenation to convert more readily available CBD into HHC, with Delta 8 THC serving as an intermediary in this conversion process.

HHC was initially discovered by American chemist Roger Adams in the 1940s, alongside CBD and Delta 8 THC. Despite its early discovery, extensive research into HHC remains limited. Some studies have suggested that certain HHC analogs may slow tumor growth in breast cancer patients, while others report its potential to relieve aches and pains. However, it’s crucial to note that these studies did not involve human subjects.

Under the 2018 Farm Bill, HHC is considered a legal hemp derivative in the United States, a legality reaffirmed by the 9th U.S. Circuit Court of Appeals in 2022. HHC products like highly potent HHC extract offer a milder high compared to Delta 9 THC, making it an appealing choice for those seeking a marijuana-like experience with reduced intensity. Users often describe its effects as uplifting and dreamy, with some experiencing muscle relaxation and minor pain relief.

Potential Benefits:

While research on HHC is limited, some studies suggest that certain HHC analogs may slow tumor growth in breast cancer patients. Additionally, some users have reported pain relief and relaxation effects when using HHC.

HHCP: The Enigmatic Derivative

Hexahydrocannabiphorol, or HHCP, is another hemp cannabinoid, albeit one with an unclear natural existence. Unlike HHC, HHCP’s structure sets it apart due to its extended carbon tail. HHCP is most commonly found in cartridges, tinctures, and disposables, often in cannabinoid blends that may include THCA, THCP, and HHC itself.

While research on HHCP is scarce, its structural differences suggest a potential for increased potency compared to HHC. Users have reported powerful and long-lasting highs with HHCP, but there are conflicting claims regarding its impact on sleep quality. Given its potency, it’s advisable for new users to start with a small dose and gradually adjust as needed.

In terms of medicinal benefits, there is currently no substantial evidence to support any claims related to HHCP. Sellers may mention anti-inflammatory or anxiolytic properties, but these assertions lack scientific backing. HHCP’s safety and legality largely align with HHC, adhering to the 0.3% delta 9 THC threshold, though state regulations may vary.

Safety Considerations:

HHCP’s safety profile is relatively unknown due to limited research. It’s important to exercise caution when trying HHCP products and to adhere to recommended dosages.

HHC-O: A Complex Acetate Ester

HHC-O-acetate (HHC-O or HHCO) is the acetate ester of HHC, synthesized from HHC using acetic anhydride. Unlike HHC and HHCP, HHC-O may not naturally occur in hemp, which could present legal challenges as it doesn’t meet the criteria of the 2018 Farm Bill protecting naturally-occurring hemp cannabinoids.

HHC-O is known for its potential potency, likely surpassing regular HHC and potentially rivaling Delta 9 THC. Some users have reported a psychedelic high with HHC-O, a notable distinction from HHC’s typical effects. However, it is crucial to emphasize the potential dangers of inhaling ketene, a toxic gas that can result from thermal degradation of acetates, including HHC-O.

Given the safety concerns associated with vaping HHC-O, it is strongly discouraged. Edible forms such as strongest hhco gummies available may offer a safer alternative for those interested in exploring its effects. As with HHCP, there is a lack of substantial research on the medicinal benefits of HHC-O, and claims should be viewed with skepticism.

Comparative Summary: HHC vs. HHCP vs. HHC-O

In summary, HHC, HHCP, and HHC-O each offer distinct experiences within the world of cannabinoids. HHC provides a milder high, making it an attractive option for those seeking a gentler alternative to Delta 9 THC. HHCP appears to offer a more potent experience, potentially rivaling Delta 9 THC’s intensity. However, safety concerns and a lack of research emphasize the need for caution.

HHC-O, on the other hand, introduces a psychedelic element but also raises significant safety issues when vaped. Edible forms may provide a safer route for exploration. It’s important to note that research on these compounds is limited, and claims regarding their medicinal benefits should be approached with caution.


In conclusion, the world of cannabinoids continues to evolve, with compounds like HHC, HHCP, and HHC-O adding complexity to the landscape. As with any novel substance, it is essential for individuals to exercise prudence, prioritize safety, and stay informed about the evolving legal and scientific aspects of these compounds.

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