Published on September 20, 2023

10 Uses of Natural Honey in Human Diseases

Honey is much more than a sweet treat. This golden nectar has been used for its medicinal properties since ancient times. Modern medical research has now rediscovered the immense therapeutic potential of natural honey.

Let’s explore some of the evidence-based uses of honey in preventing and managing various human diseases and conditions.

1. Antibacterial Properties of Honey

Honey possesses potent antibacterial effects, which form the basis of its effectiveness in treating wounds and burns. Its low water content and acidic pH between 3 to 4 create an environment that inhibits microbial growth.  

Hydrogen peroxide, a major contributor to honey’s antibacterial activity, is continuously produced from the oxidation of glucose by glucose oxidase enzymes in raw honey. Certain floral varieties like Manuka honey contain additional antibacterial components like methylglyoxal. 

Thanks to these properties, clinical evidence supports the use of honey in treating diabetic foot ulcers, venous leg ulcers, first- to second-degree burns, and post-operative wounds (3). When used as a dressing, natural honey reduces healing time, prevents infection, and minimizes scarring.

Now, as we delve further into the world of honey’s therapeutic wonders, it’s essential to remember that not all honey is created equal. Some varieties, like the lesser-known but equally extraordinary white honey, possess unique properties that deserve exploration.

2. Honey as an Antioxidant Powerhouse

Honey also contains flavonoids, phenolic acids, carotenoid derivatives, amino acids, proteins, and enzymes that act as antioxidants. The processing of honey increases antioxidant activity as Maillard reaction products are formed.

These antioxidants neutralize damaging free radicals in the body that are linked to chronic diseases. Polyphenols in honey, like pinobanksin, pinocembrin, and chrysin, demonstrate significant radical scavenging capacity.

Regular consumption of natural honey raises antioxidants in the plasma and may provide protection from oxidative stress and chronic inflammation. This antioxidant power of honey can potentially help prevent cancer, heart disease, arthritis, neurological decline, and diabetes complications.

The chart highlights the variations in antibacterial activity among various honey varieties. Notably, Manuka honey leads with a hydrogen peroxide production rate of 349 µM/min/g, followed by buckwheat honey at 285 µM/min/g. 

Wildflower, clover, and acacia honey varieties exhibit lower but still substantial levels of hydrogen peroxide production.

3. Honey in Digestive Health 

Natural honey can alleviate several digestive issues. Its antioxidant and antimicrobial attributes are useful in treating peptic ulcers caused by H. Pylori bacteria. Research also shows honey reduces the severity of diarrhea in cases of gastroenteritis.

Due to its prebiotic fructooligosaccharides content, honey promotes the growth of beneficial Bifidobacteria and Lactobacilli in the gut. This helps maintain intestinal permeability and gut health.

Furthermore, honey is an effective treatment for reflux symptoms in chronic laryngitis patients. It displays greater therapeutic efficacy than conventional reflux medications.

4. Honey’s Role in Respiratory Diseases

Honey has traditionally been used to treat coughs and sore throats. Multiple studies now confirm its benefits in respiratory conditions.

A meta-analysis found honey decreases the frequency and severity of coughs more effectively than diphenhydramine, dextromethorphan, or placebo in children. Thanks to its antimicrobial and anti-inflammatory properties, honey also reduces symptoms of upper respiratory tract infections. 

Research indicates that long-term ingestion of honey reduces seasonal allergies. It may also inhibit Nitric Oxide release implicated in asthma pathology and help with post-infectious cough in Bronchiectasis patients.

5. Honey in Cardiovascular Health  

Emerging evidence suggests raw honey can support heart health and help reduce cardiovascular disease risk factors. 

Studies demonstrate that consuming 70-80 grams of natural honey for 30 days significantly lowers LDL cholesterol, blood triglycerides, C-reactive protein, homocysteine, fasting blood glucose, and oxidative stress markers.

Thanks to its antioxidant flavonoids, honey also inhibits LDL oxidation and artery wall damage, reducing plaque buildup. Manuka honey, especially, exhibits anti-thrombotic activity, preventing blood clot formation.

Overall, incorporating raw honey into a balanced diet may benefit cardiovascular health through multifaceted mechanisms.

6. Honey’s Anti-inflammatory Effects 

The antioxidant constituents of honey exhibit significant anti-inflammatory capabilities. Honey is shown to decrease inflammatory oxidative damage and markers like C-reactive proteins, homocysteine, and cytokines.

This anti-inflammatory attribute can alleviate conditions like arthritis, inflammatory bowel diseases, atherosclerosis, and antibiotic-induced gut inflammation. Oral consumption and topical application of natural honey both demonstrate anti-inflammatory properties.

7. Honey in Diabetes Management

For individuals with diabetes, honey has a lower glycemic index than refined sugars, meaning it raises blood glucose levels more gradually. However, moderation is still key.

Human trials show that replacing sugar with honey leads to lower glycosylated hemoglobin levels and fasting blood glucose in diabetics. It also increases plasma antioxidant capacity and suppresses inflammation.

However, honey remains a source of carbohydrates that raise blood sugar levels. Diabetics should be mindful of portion sizes and monitor glucose carefully when consuming honey.

8. Honey’s Role in Boosting Immunity 

Raw honey contains many vitamins, minerals, and enzymes that may enhance immune function. Its antioxidant properties also help mitigate oxidative damage from free radicals, preserving white blood cell immunity.

Specific compounds in honey like methylglyoxal, hydrogen peroxide, and proteinaceous bee products stimulate and modulate immune responses. The immunomodulatory effects can potentially protect against diseases. 

However, larger human studies are still needed to confirm the definitive immune-boosting benefits of natural honey.

9. Honey in Dermatology 

Applied topically, honey displays therapeutic effects for various inflammatory skin disorders and wounds. 

Its antimicrobial and anti-inflammatory properties make honey a highly effective remedy for conditions like psoriasis, eczema, acne, burns, and skin ulcers. Honey helps hydrate, soothe inflammation, stimulate tissue regeneration, and prevent bacterial overgrowth.

Honey also accelerates wound contraction in full-thickness burns, with greater efficacy than silver sulfadiazine treatment. When used as a dressing, honey promotes moist healing with minimal scarring.

10. Honey’s Potential in Neurological Diseases  

Early research indicates honey may offer protection against certain neurological diseases. In clinical studies, regular honey intake improves immediate memory recall in postmenopausal women. 

Animal studies also demonstrate honey antioxidants delay the onset of drug-induced dementia, potentially slowing cognitive decline. Honey polyphenols are hypothesized to combat neuronal oxidative stress implicated in diseases like Alzheimer’s and Parkinson’s.

However, more human trials are warranted to establish the neurological health benefits of natural honey consumption.

Frequently Asked Questions (FAQs)

Is it safe to consume honey daily for its medicinal properties?

In moderation, daily honey consumption is considered safe for most people. About 1-2 tablespoons per day balance its health benefits with sugar and calorie intake. However, children under one and people with diabetes or honey allergy should exercise caution.

Are certain types of honey more potent in treating diseases?

Some varieties like Manuka and buckwheat honey have higher levels of antioxidants. Darker raw, unfiltered honey generally retains more beneficial antibacterial and anti-inflammatory properties.

Can honey interact with medications or other treatments?

Honey can interact with certain antibiotics. People on medications or treatment plans should consult their healthcare provider before regularly ingesting honey for medicinal purposes.

Key Takeaway

Thanks to its multifaceted therapeutic properties, honey has served as nature’s medicine for centuries.

While more research is still emerging, current evidence supports honey’s antimicrobial, antioxidant, anti-inflammatory, and wound-healing abilities. When used responsibly, it can be a powerful tool in your wellness toolkit.


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