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Published on June 23, 2023

From Blues to Bliss: Unleash Your Inner Happiness with Top Mood-Boosting Supplements

Feeling down or struggling with mood issues? This has become all too common in today’s fast-paced world. Thankfully, there is a growing interest in finding natural solutions to boost our mood and enhance overall well-being. In this article, we delve into the realm of dietary supplementation and explore the top mood boosting supplements that have gained popularity among individuals seeking to uplift their spirits. 

While lifestyle changes and therapy play crucial roles in managing mood, mood enhancing supplements like NextEVo’s Ashwagandha, Maca, Ginkgo Biloba and others are a good addition to support your emotional health. Discover the science behind their effectiveness, unlock the potential of natural calm gummies and experience the transformative power they hold!

Top Supplements to Elevate Your Mood and Uplift Your Spirits


Magnesium, a vital mineral found abundantly in the human body, plays a significant role in promoting positive mood and thinking. Magnesium facilitates the production and release of serotonin, which is often referred to as the “feel-good” neurotransmitter. Serotonin helps regulate mood, and low levels have been associated with symptoms of depression and anxiety.

Furthermore, magnesium acts as a natural antagonist to the NMDA receptor, which releases glutamate, an excitatory neurotransmitter. By regulating NMDA receptor activity, magnesium maintains the balance between excitatory and inhibitory neurotransmission, preventing excessive neuronal firing that can cause anxiety and irritability.


Theanine is an amino acid which increases the production of gamma-aminobutyric acid (GABA) neurotransmitter that contributes to feelings of relaxation. Ir inhibits the activity of excitatory neurotransmitters, resulting in a calming effect on the brain. Theanine stimulates the release of GABA, leading to a reduction in anxiety and stress, and ultimately promoting a more positive mood.


One of the most outstanding herbs for calm & relaxation is ashwagandha, a natural adaptogen which helps promote the feeling of happiness. Ashwagandha helps regulate stress and anxiety by reducing cortisol levels and modulating the body’s stress response. Furthermore, ashwagandha supports neurotransmitter balance, particularly the modulation of serotonin and gamma-aminobutyric acid (GABA).

Rhodiola Rosea

If you are looking for mood-enhancing herbs, pay your attention to Rhodiola Rosea. It is often used in teas and in the production of supplements for mood support. One of the key ways Rhodiola Rosea exerts its effects is by influencing the activity of neurotransmitters in the brain. It enhances the availability and transport of serotonin, dopamine and norepinephrine. Serotonin controls your mood and is responsible for happiness, dopamine is involved in motivation, reward, and pleasure, while norepinephrine plays a role in attention and focus.

Lemon Balm

The process through which lemon balm works to support mood and thinking involves various methods:

  • Firstly, it interacts with GABA receptors in the brain that helps regulate anxiety and stress levels. 
  • Secondly, it inhibits the acetylcholinesterase enzyme, supporting cognitive processes such as attention, focus, and memory.
  • Thirdly, lemon balm protects brain cells from oxidative stress with its antioxidants. 

St. John’s Wort

St. John’s Wort is one of the most ancient herbs that calm anxiety and reduce stress. It modulates the activity of the hypothalamic-pituitary-adrenal (HPA) axis, which plays a role in the body’s response to stress, thus promoting a more balanced stress response.

Plus, St. John’s Wort increases the availability of serotonin, dopamine, and norepinephrine in the brain, promoting improved mood regulation, emotional well-being, and enhanced cognitive function.

Bacopa Herb 

Bacopa is an adaptogenic herb which assists the body in adapting to stress and maintaining emotional balance. Bacopa helps regulate the stress response, reducing the release of stress hormones and promoting a more calm and positive mental state. 

Moreover, Bacopa can influence the activity of certain enzymes, such as choline acetyltransferase and acetylcholinesterase. They are responsible for supporting cognitive function and positive mood.

Holy Basil

Don’t confuse culinary basil and holy basil. The last one has gained prominence in modulating stress response, as it regulates the release of stress hormones, such as cortisol, which can negatively impact mood and cognitive function. This herb also helps promote blood flow and oxygen delivery to the brain, which has a positive impact on your cognitive function.

Maca Root

Maca is among the most popular calm herbs which soothe your nerves and restore your mental balance. As other herbs listed above, maca influences neurotransmitters in the brain, including dopamine, serotonin, and norepinephrine, which are responsible for the feeling of happiness.

Moreover, maca is rich in essential vitamins, minerals, and antioxidants which support optimal brain function, providing the necessary building blocks for neurotransmitter synthesis and neural communication. 

Astragalus Root

This Chinese herb contains bioactive compounds that support neuroprotective effects. These compounds help protect brain cells from damage and promote their survival.  Astragalus promotes HPA axis balance, which is essential for mitigating the negative impact of stress on mood and cognitive function, leading to a more positive mindset.

Valerian Root

Valerian is a very popular herb which is used worldwide in the production of supplements to boost mood. First of all, valerian root is highly helpful in regulating sleep patterns. It is involved in the synthesis of serotonin and melatonin which are crucial for regulating a sleep-wake cycle.

Valerian also increases the levels of GABA, a neurotransmitter that promotes relaxation and mental wellness. A little bit of Zen in every bite!

Ginkgo Biloba

One of the primary ways Ginkgo Biloba exerts its effects is through its vasodilatory properties. It helps dilate blood vessels and improve blood flow, including in the brain. By enhancing blood circulation, Ginkgo Biloba ensures that the brain receives an adequate supply of oxygen and nutrients, which is essential for optimal cognitive function and positive mood.

Final Thoughts: Top Mood Boosting Supplements 

Supporting our mood and emotional well-being is of paramount importance in today’s world full of stress and negative influences. Incorporating mood-boosting supplements like Magnesium, Ashwagandha, Maca, Valeriana or Ginkgo Biloba into our daily routines can be a valuable addition to restore your mental equilibrium and promote the feeling of relaxation. 

Let your mental energy soar and put stress at bay: by embracing these natural herbs, you empower yourself to take charge of our mental well-being and nurture a positive mindset. 

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