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Published on June 24, 2023

The Impact of Low Testosterone and Mental Health

When we think of testosterone, we often associate it with characteristics such as sexual function, libido, and muscle mass. However, what many people may not realize is that testosterone also plays a significant role in mental health. Low levels of testosterone can have a profound effect on our mental and emotional well-being. In this article, we will explore the connection between low testosterone and its impact on mental health, delving into the symptoms, indirect effects, and potential treatments.

Understanding Testosterone and its Role in Mental Health

Testosterone, primarily produced in the testicles, is a vital hormone that affects various aspects of our health. While it is commonly associated with sexual and reproductive functions, testosterone also influences other areas, including mental health. 

The brain contains testosterone receptors, and when testosterone levels are lower than normal, these receptors can be left unstimulated, leading to mood swings, irritability, stress, anxiety, and even depression. 

This collection of symptoms, known as “andropause,” is similar to menopause in women but occurs more gradually in men. It is essential to recognize the potential impact of low testosterone on mental health to seek appropriate treatment and support.

The Indirect Effects of Low Testosterone on Mental Health

In addition to its direct impact on the brain, low testosterone can also indirectly affect mental and emotional health. 

For example, low testosterone levels can lead to sexual health issues such as a loss of libido or erectile dysfunction. 

These problems can cause anxiety and stress, further exacerbating mood disturbances. 

Additionally, low testosterone can disrupt sleep patterns, leading to fatigue, which can contribute to moodiness and cognitive difficulties. It is crucial to understand these indirect effects to fully comprehend the scope of low testosterone’s impact on mental health. 

This then compounds on a hormonal level, as the body requires sleep to remove cortisol, the stress hormone, this then in turn causes further disruptions to sleep and further disruption to testosterone production. 

To top it all off, dropping T levels can cause weight gain and muscle loss, which then of course has a negative impact on a persons self image and overall health. 

Recognizing the Similarities between Low Testosterone and Mental Health Disorders

The symptoms of low testosterone often overlap with those of mental health disorders such as depression and anxiety. 

Fatigue, anxiety, depression, irritability, difficulty concentrating, memory difficulties, insomnia, and low libido are all common symptoms associated with both low testosterone and these mental health conditions. This similarity in symptoms can make it challenging to differentiate between low testosterone and mental health disorders. 

Therefore, a comprehensive evaluation by a healthcare professional is crucial to accurately diagnose and treat the underlying cause of these symptoms, personal tests for depression can be helpful to get the ball rolling, but are no substitute.

The Link Between Testosterone and Depression

Depression is a prevalent mental health condition that affects millions of people worldwide. 

While it has various causes, some studies suggest a potential link between low testosterone and depression. Research has shown that individuals with low testosterone levels, particularly middle-aged men, are more likely to experience depressive symptoms. 

The association between low testosterone and depression is further supported by studies that found low levels of bioavailable testosterone in men with depression

These findings highlight the importance of considering testosterone levels when evaluating and treating individuals with depression.

To make matters worse, both conditions exacerbate one another. Stress and broken sleep are leading causes of low testosterone levels. So, there is often a direct link between mental health and testosterone. From that point the symptoms of low testosterone can of course make mental health worse as we have already discussed.

Seeking Professional Help and Treatment Options

If you are experiencing symptoms such as fatigue, anxiety, depression, low libido, or other mental health concerns, it is crucial to consult with a healthcare professional. They can evaluate your testosterone levels through blood tests and determine if low testosterone is contributing to your symptoms. 

Depending on the diagnosis, treatment options may include testosterone replacement therapy, lifestyle changes, or other interventions tailored to your specific needs. It is important to address both the physical and mental aspects of your well-being to achieve optimal health.

The first port of call should always be to take a good look in the mirror and see if there are any obvious lifestyle changes you can make. 

As much as it is sometimes difficult to hear and even more difficult to start. If you’re not eating well, not getting enough exercise and sleep the best thing you can do is change that immediately.

Exercise is fantastic for mental health, can improve sleep patterns and there are even some studies that show it can by itself raise testosterone levels. But, beyond that being a healthy weight has been shown repeatedly to improve overall mental well being.

Testosterone Replacement Therapy as a Potential Solution

Testosterone replacement therapy (TRT) has shown promise in alleviating depressive symptoms associated with low testosterone levels. 

Several clinical trials have demonstrated that TRT can have a moderate antidepressant effect compared to a placebo, resulting in clinically significant reductions in depressive symptoms. 

Middle-aged men with low testosterone levels tend to benefit the most from TRT, particularly those with less severe depression. It is worth noting that TRT may also be beneficial for individuals experiencing sexual dysfunction as a side effect of traditional depression treatments. There are various types of TRT available and you read more about them here.

Testosterone Supplements for Mental Health

There are a lot of natural supplements that boost testosterone, or at least claim to. And there is some truth to the science here, even if it’s not quite as dramatic as a lot of the sellers would have you believe. We actually caught up with Dr Mark Watson M.D. of Centertrt.org for this question as he’s generally considered to be one of the leading experts when it comes to phytogenic compounds and their effects on hormones. 

He told us the following. “Testosterone supplements tend to work in one of two ways. The first being that they address vitamin deficiencies which can cause a drop in hormone production. For example, even a low or (subclinical deficiency) of zinc can cause testosterone levels to plummet and studies have shown supplementing this can be effective for treating low test in zinc deficient men, some vitamins and minerals have even been shown to boost testosterone levels, but the science is a bit more mixed than that around deficiencies. And some of these deficiencies, like in vitamin D can exacerbate mental health issues and lower testosterone levels causing a doubling effect in this case” 

He continued to talk about herbal testosterone boosters saying “when it comes to herbal compounds, there’s some promising evidence around Ashwagandha, which helps the body purge cortisol (the stress hormone), has been shown to promote sleep, another issue that can cause mental health problems, as well as raise T levels although the evidence for the first two is actually better than the latter. There’s a few other interesting compounds, particularly in Panax Ginseng and Fenugreek. Unfortunately, there’s also a lot of spurious claims from supplement manufacturers and promoting a healthy lifestyle overall should be the first port of call. But, there is no doubt that looking at what you’re putting in your body is important for testosterone and mental health.”

Taking a Holistic Approach to Mental Health

While testosterone replacement therapy can be a helpful intervention, it is essential to take a holistic approach to mental health. Factors such as stress, diet, exercise, sleep, and overall lifestyle can all impact testosterone levels and mental well-being. Incorporating stress-management techniques, regular physical activity, and a balanced diet can support healthy testosterone production and improve mental health. Additionally, seeking support from mental health professionals, joining support groups, and engaging in therapy can provide valuable tools for managing mental health concerns.


Testosterone plays a crucial role in mental health, and low levels of this hormone can have a significant impact on our well-being. Understanding the connection between low testosterone and mental health symptoms is essential for accurate diagnosis and appropriate treatment. 

It should also be noted that low testosterone in women can also have similar effects, but it is less likely to be noticed.

If you are experiencing symptoms related to low testosterone or mental health disorders, it is important to seek professional help. Through a comprehensive evaluation, healthcare professionals can determine the underlying cause of your symptoms and develop a personalized treatment plan to improve your mental and emotional well-being. Remember, addressing both physical and mental aspects of health is essential for achieving optimal overall well-being.

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